Homogenous mixing of propofol emulsion into an infusion solution
نویسندگان
چکیده
منابع مشابه
Investigation of electrokinetic mixing in 3D non-homogenous microchannels
A numerical study of 3D electrokinetic flows through micromixers was performed. The micromixers considered here consisted of heterogeneous rectangular microchannels with prescribed patterns of zeta-potential at their walls. Numerical simulation of electroosmotic flows within heterogeneous channels requires solution of the Navier-Stokes, Ernest-Plank and species concentration equations. It is kn...
متن کاملCorrection of target-controlled infusion following wrong selection of emulsion concentrations of propofol
BACKGROUND We investigated the correction methods following wrong-settings of emulsion concentrations of propofol as a countermeasure against erroneous target-controlled infusions (TCI). METHODS TCIs were started with targeting 4.0 µg/ml of effect-site concentration (Ceff) of propofol, and the emulsion concentrations were selected for 2.0% instead of 1.0% (FALSE1-2, n = 24), or 1.0% instead o...
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Package insert information provided with propofol advises prompt administration following its drawing-up. This study has examined the delays which occur between drawing-up and administration of propofol in clinical practice and the incidence of bacterial contamination occurring under such conditions. Two hundred and fifty-four clinical uses of propofol were examined. Mean elapsed times (range) ...
متن کاملPharmacokinetics and pharmacodynamics of propofol microemulsion and lipid emulsion after an intravenous bolus and variable rate infusion.
BACKGROUND The aim of this trial was to evaluate the induction and recovery characteristics of microemulsion propofol (Aquafol; Daewon Pharmaceutical Co., Ltd., Seoul, Korea). Pharmacokinetics, pharmacodynamics, and safety profile were investigated. Lipid emulsion propofol (Diprivan; AstraZeneca, London, United Kingdom) was used as a comparator. METHODS Thirty-one healthy volunteers aged 20-7...
متن کاملPropofol infusion syndrome.
The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol.l(-1)), rhabdomyolysis, hyperlipidaemia, and enlarged or fatty liver. There is an association between PRIS and propofol infusions at doses higher than 4 mg.kg(-1).h(-1) for greater than 48 h d...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1999
ISSN: 0003-2409
DOI: 10.1046/j.1365-2044.1999.1013u.x